Events and Things to do in Defiance, MO

Search for something you love or check out popular events in your area.

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Trap & Taste Black Tie Winery Tour
Saturday at 11:45 AM
East St. Louis · DraftKings at Casino Queen
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Trap & Taste Black Tie Winery Tour
Saturday at 11:45 AM
East St. Louis · DraftKings at Casino Queen
She Wakes 2027
Fri, Apr 9, 4:30 PM + 1 more
Columbia · Life Community Church
She Wakes 2027
Fri, Apr 9, 4:30 PM + 1 more
Columbia · Life Community Church
Hermann Hustle Scavenger Hunt
Today at 11:00 AM + 225 more
Hermann · Espresso Laine
Hermann Hustle Scavenger Hunt
Today at 11:00 AM + 225 more
Hermann · Espresso Laine
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Applying Your Style for Greater Impact
Fri, May 8, 11:30 AM
Alton · The Wedge Innovation Center
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Applying Your Style for Greater Impact
Fri, May 8, 11:30 AM
Alton · The Wedge Innovation Center
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4th Annual Trivia (Music Themed)
Saturday at 7:00 PM
Alton · Owl's Club
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4th Annual Trivia (Music Themed)
Saturday at 7:00 PM
Alton · Owl's Club
Comedy Night w/ dinner included
Fri, May 8, 6:00 PM
Festus · Taytros Bar & Bistro
Comedy Night w/ dinner included
Fri, May 8, 6:00 PM
Festus · Taytros Bar & Bistro
L'OREAL Professionel Balayage, Foils, and Glossing
Mon, May 11, 10:00 AM
Godfrey · Saloncentric of Godfrey
L'OREAL Professionel Balayage, Foils, and Glossing
Mon, May 11, 10:00 AM
Godfrey · Saloncentric of Godfrey
Just added
Passion Meets the Body in Nice Social
Sat, May 23, 9:00 PM
Alton · Beyond Taste
Just added
Passion Meets the Body in Nice Social
Sat, May 23, 9:00 PM
Alton · Beyond Taste
Friday Night Dinner Drag Show
Fri, May 15, 7:00 PM
Alton · 602 Belle St
Friday Night Dinner Drag Show
Fri, May 15, 7:00 PM
Alton · 602 Belle St
May Paint & Sip Afternoon at Bubby's
Sun, May 17, 12:00 PM
Alton · 602 Belle St
May Paint & Sip Afternoon at Bubby's
Sun, May 17, 12:00 PM
Alton · 602 Belle St
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Shamanic Healing Experience & Ritual Apothecary
Saturday at 1:00 PM + 7 more
Alton · YWCA Southwestern Illinois
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Shamanic Healing Experience & Ritual Apothecary
Saturday at 1:00 PM + 7 more
Alton · YWCA Southwestern Illinois
Swifties Vs Carpenters Drag Brunch
Sun, May 31, 11:00 AM
Alton · 602 Belle St
Swifties Vs Carpenters Drag Brunch
Sun, May 31, 11:00 AM
Alton · 602 Belle St
Mississippi Mornings: Nine PBS Playdate in Alton!
Sat, May 30, 9:30 AM
Alton · Alton Riverfront Amphitheater
Mississippi Mornings: Nine PBS Playdate in Alton!
Sat, May 30, 9:30 AM
Alton · Alton Riverfront Amphitheater
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Paranormal Investigation at the Bluff Grange
Fri, May 8, 8:00 PM
Millstadt · Bluff Grange
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Paranormal Investigation at the Bluff Grange
Fri, May 8, 8:00 PM
Millstadt · Bluff Grange
Just added
Summer AI Learnathon
Fri, Jun 5, 8:30 AM
Alton · The Wedge Innovation Center
Just added
Summer AI Learnathon
Fri, Jun 5, 8:30 AM
Alton · The Wedge Innovation Center
Rock the Hops 2026
Sat, Aug 8, 2:00 PM
Alton · Alton
Rock the Hops 2026
Sat, Aug 8, 2:00 PM
Alton · Alton
Little Mania Midget Wrestling All-Stars: World Tour in Columbia, IL!
Sun, Aug 23, 7:30 PM
Columbia · Power Haus
Little Mania Midget Wrestling All-Stars: World Tour in Columbia, IL!
Sun, Aug 23, 7:30 PM
Columbia · Power Haus
Spirit of St. Louis Chorus Spring Show
Sat, May 9, 7:00 PM
De Soto · Knights of Columbus
Spirit of St. Louis Chorus Spring Show
Sat, May 9, 7:00 PM
De Soto · Knights of Columbus
Celebrate Mom in Style at Our Annual Mother's Day Brunch!
Sun, May 10, 11:00 AM
Alton · Vera Lee - Meeting & Event Venue
Celebrate Mom in Style at Our Annual Mother's Day Brunch!
Sun, May 10, 11:00 AM
Alton · Vera Lee - Meeting & Event Venue
Almost full
Althoff Summer Drama Camp # 1 2026 - Annie, KIDS
Mon, Jun 1, 9:00 AM
Belleville · Althoff Catholic High School
Almost full
Althoff Summer Drama Camp # 1 2026 - Annie, KIDS
Mon, Jun 1, 9:00 AM
Belleville · Althoff Catholic High School

Trends in Defiance

Explore more trends

Frequently asked questions about Defiance

What are the best events to attend?

According to Eventbrite, the best events are:

She Wakes 2027

Applying Your Style for Greater Impact

Comedy Night w/ dinner included

L'OREAL Professionel Balayage, Foils, and Glossing

Which events are currently trending in Defiance?

The trending searches this month in Defiance are:

bloom

wedding open house

mo ladies confrence

Which events are coming up?

Discover the best events happening soon – you don't want to miss them:

Hermann Hustle Scavenger Hunt

Trap & Taste Black Tie Winery Tour

Shamanic Healing Experience & Ritual Apothecary

4th Annual Trivia (Music Themed)

Trap & Taste Black Tie Winery Tour

Trap & Taste Black Tie Winery Tour

She Wakes 2027

She Wakes 2027

Hermann Hustle Scavenger Hunt

Hermann Hustle Scavenger Hunt

Applying Your Style for Greater Impact

Applying Your Style for Greater Impact

4th Annual Trivia (Music Themed)

4th Annual Trivia (Music Themed)

Comedy Night w/ dinner included

Comedy Night w/ dinner included

L'OREAL Professionel Balayage, Foils, and Glossing

L'OREAL Professionel Balayage, Foils, and Glossing

Passion Meets the Body in Nice Social

Passion Meets the Body in Nice Social

Friday Night Dinner Drag Show

Friday Night Dinner Drag Show

May Paint & Sip Afternoon at Bubby's

May Paint & Sip Afternoon at Bubby's

Shamanic Healing Experience & Ritual Apothecary

Shamanic Healing Experience & Ritual Apothecary

Swifties Vs Carpenters Drag Brunch

Swifties Vs Carpenters Drag Brunch

Mississippi Mornings: Nine PBS Playdate in Alton!

Mississippi Mornings: Nine PBS Playdate in Alton!

Paranormal Investigation at the Bluff Grange

Paranormal Investigation at the Bluff Grange

Summer AI Learnathon

Summer AI Learnathon

Rock the Hops 2026

Rock the Hops 2026

Little Mania Midget Wrestling All-Stars: World Tour in Columbia, IL!

Little Mania Midget Wrestling All-Stars: World Tour in Columbia, IL!

Spirit of St. Louis Chorus Spring Show

Spirit of St. Louis Chorus Spring Show

Celebrate Mom in Style at Our Annual Mother's Day Brunch!

Celebrate Mom in Style at Our Annual Mother's Day Brunch!

Althoff Summer Drama Camp # 1 2026 - Annie, KIDS

Althoff Summer Drama Camp # 1 2026 - Annie, KIDS

Things to do around Defiance

Trends in Defiance

1. Bloom

2. Wedding open house

3. Mo ladies confrence

What are the best events to attend?

Which events are currently trending in Defiance?

Which events are coming up?